https://example.com/tags/bioinformatics/BioinformaticsHugoBlox Kit (https://hugoblox.com)en-usMon, 12 Jul 2021 11:10:44 -0400https://example.com/media/logo.svghttps://example.com/tags/bioinformatics/https://example.com/projects/mmappr2/Mon, 12 Jul 2021 11:10:44 -0400https://example.com/projects/mmappr2/<p>MMAPPR2 maps mutations resulting from pooled RNA-seq data from the F2 cross of forward genetic screens. It accepts aligned BAM files as well as a reference genome as input and identifies loci of high sequence disparity between the control and mutant RNA sequences. It is significantly faster than its predecessor ( ) and enhances its functionality by improving mutation localization and integrating with Ensembl&rsquo;s Variant Effect Predictor, outputting a ranked list of candidate mutations.</p>